:root {
  color-scheme: dark;
  --bg: #10070a;
  --bg-soft: #1a0c11;
  --panel: #241117;
  --panel-2: #321820;
  --text: #fff8f7;
  --soft: #e4c8c5;
  --muted: #b99390;
  --line: rgba(255, 225, 220, 0.14);
  --line-strong: rgba(255, 225, 220, 0.3);
  --red: #ff667a;
  --red-dark: #c72e49;
  --amber: #ffc75a;
  --cyan: #69d7ea;
  --green: #67deb2;
  --violet: #c0a7ff;
  --danger-soft: rgba(255, 102, 122, 0.12);
  --shadow: 0 24px 70px rgba(0, 0, 0, 0.34);
  --radius: 22px;
  --radius-sm: 14px;
  --max: 1220px;
  --sans: Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;
  --mono: ui-monospace, SFMono-Regular, Menlo, Monaco, Consolas, monospace;
}

html[data-theme="light"] {
  color-scheme: light;
  --bg: #ffffff;
  --bg-soft: #fff4f3;
  --panel: #ffffff;
  --panel-2: #fbe7e6;
  --text: #301419;
  --soft: #5f353a;
  --muted: #79555a;
  --line: #d1a7aa;
  --line-strong: #a9757b;
  --red: #b4233f;
  --red-dark: #8e1730;
  --amber: #855400;
  --cyan: #006b7d;
  --green: #087a55;
  --violet: #5946c7;
  --danger-soft: #fff0f2;
  --shadow: 0 18px 50px rgba(112, 35, 48, 0.12);
}

html.a11y-contrast {
  color-scheme: dark;
  --bg: #000000;
  --bg-soft: #080808;
  --panel: #0a0a0a;
  --panel-2: #171717;
  --text: #ffffff;
  --soft: #ffffff;
  --muted: #e5e5e5;
  --line: #ffffff;
  --line-strong: #ffffff;
  --red: #ff8797;
  --amber: #ffd86a;
  --cyan: #87efff;
  --green: #8affcf;
  --violet: #d6c7ff;
  --shadow: none;
}

* { box-sizing: border-box; }
html { scroll-behavior: smooth; }
body { margin: 0; color: var(--text); background: var(--bg); font: 16px/1.58 var(--sans); }
body.focus-mode .section:not(:target), body.focus-mode .safety-band, body.focus-mode footer { opacity: 0.38; }
body.focus-mode .section:target { opacity: 1; }
button, input, select { font: inherit; }
a { color: inherit; }
button, a, input, select { -webkit-tap-highlight-color: transparent; }
:where(button, a, input, select, [tabindex]):focus-visible { outline: 3px solid var(--amber); outline-offset: 3px; }
.wrap { width: min(var(--max), calc(100% - 32px)); margin-inline: auto; }
.skip-link { position: fixed; z-index: 100; top: -70px; left: 14px; padding: 10px 14px; border-radius: 10px; color: var(--bg); background: var(--text); font-weight: 900; }
.skip-link:focus { top: 12px; }

.topbar { position: sticky; z-index: 50; top: 0; border-bottom: 1px solid var(--line); background: rgba(16, 7, 10, 0.94); backdrop-filter: blur(18px); }
html[data-theme="light"] .topbar { background: rgba(255, 255, 255, 0.95); }
.nav-shell { min-height: 76px; display: flex; align-items: center; justify-content: space-between; gap: 24px; }
.brand { min-width: max-content; display: flex; align-items: center; gap: 11px; text-decoration: none; }
.brand-icon { width: 46px; height: 46px; display: grid; place-items: center; border: 1px solid var(--line-strong); border-radius: 15px; background: var(--panel-2); font-size: 1.35rem; }
.brand strong, .brand small { display: block; }
.brand strong { letter-spacing: -0.02em; }
.brand small { margin-top: 2px; color: var(--muted); font: 0.66rem/1.2 var(--mono); letter-spacing: 0.08em; text-transform: uppercase; }
.nav-links { display: flex; align-items: center; justify-content: flex-end; gap: 5px; flex-wrap: wrap; }
.nav-links a, .control-button { padding: 8px 10px; border: 1px solid transparent; border-radius: 10px; color: var(--soft); background: transparent; text-decoration: none; font-size: 0.82rem; font-weight: 750; cursor: pointer; }
.nav-links a:hover, .control-button:hover, .control-button[aria-pressed="true"] { color: var(--text); border-color: var(--line-strong); background: var(--panel-2); }
.official-strip { padding: 8px 0; color: #2b070e; background: var(--red); }
.official-strip .wrap { display: flex; justify-content: space-between; gap: 18px; font-size: 0.78rem; }
.official-strip strong { text-transform: uppercase; letter-spacing: 0.06em; }

.hero { padding: 78px 0 62px; }
.hero-grid { display: grid; grid-template-columns: minmax(0, 1.35fr) minmax(300px, 0.65fr); gap: 44px; align-items: center; }
.eyebrow { display: inline-block; color: var(--red); font: 800 0.73rem/1.2 var(--mono); letter-spacing: 0.1em; text-transform: uppercase; }
h1, h2, h3, p { margin-top: 0; }
h1 { max-width: 850px; margin-bottom: 22px; font-size: clamp(2.8rem, 7vw, 6.1rem); line-height: 0.98; letter-spacing: -0.058em; }
h1 em { display: block; color: var(--red); font-style: normal; }
h2 { margin-bottom: 0; font-size: clamp(2rem, 4.2vw, 3.5rem); line-height: 1.03; letter-spacing: -0.045em; }
h3 { line-height: 1.18; letter-spacing: -0.02em; }
.hero-lead { max-width: 780px; color: var(--soft); font-size: 1.18rem; }
.hero-actions { display: flex; gap: 10px; flex-wrap: wrap; margin: 28px 0 16px; }
.button { min-height: 44px; display: inline-flex; align-items: center; justify-content: center; padding: 10px 15px; border: 1px solid var(--line-strong); border-radius: 12px; color: var(--text); background: var(--panel); text-decoration: none; font-weight: 850; cursor: pointer; }
.button:hover { transform: translateY(-1px); border-color: var(--red); }
.button-primary { color: #2b070e; border-color: var(--red); background: var(--red); }
.button-ghost { color: var(--muted); background: transparent; }
.microcopy { max-width: 720px; color: var(--muted); font-size: 0.82rem; }
.red-flag-card { position: relative; overflow: hidden; padding: 28px; border: 1px solid rgba(255, 102, 122, 0.55); border-radius: var(--radius); background: linear-gradient(145deg, var(--danger-soft), var(--panel)); box-shadow: var(--shadow); }
.red-flag-card::after { content: ""; position: absolute; width: 160px; height: 160px; top: -80px; right: -70px; border-radius: 50%; background: rgba(255, 102, 122, 0.18); filter: blur(8px); }
.red-flag-card > * { position: relative; z-index: 1; }
.red-flag-card strong { display: block; margin: 13px 0; color: var(--red); font-size: 1.28rem; line-height: 1.25; }
.red-flag-card ul { margin: 16px 0 0; padding-left: 20px; color: var(--soft); }
.pulse-dot { display: inline-block; width: 11px; height: 11px; border-radius: 50%; background: var(--red); box-shadow: 0 0 0 8px rgba(255, 102, 122, 0.1); }

.safety-band { border-block: 1px solid var(--line); background: var(--bg-soft); }
.safety-grid { display: grid; grid-template-columns: repeat(4, 1fr); }
.safety-grid div { padding: 22px; border-right: 1px solid var(--line); }
.safety-grid div:last-child { border-right: 0; }
.safety-grid b, .safety-grid span { display: block; }
.safety-grid b { color: var(--red); }
.safety-grid span { margin-top: 6px; color: var(--soft); font-size: 0.86rem; }

.section { padding: 86px 0; }
.section-tint { border-block: 1px solid var(--line); background: var(--bg-soft); }
.section-heading { display: flex; justify-content: space-between; align-items: end; gap: 36px; margin-bottom: 34px; }
.section-heading > p { max-width: 550px; margin-bottom: 2px; color: var(--soft); }
.how-to-section { padding-block: 68px; }
.how-to-grid { display: grid; grid-template-columns: repeat(5, minmax(0, 1fr)); gap: 12px; margin: 0; padding: 0; list-style: none; }
.how-to-grid a { min-height: 100%; display: flex; gap: 12px; padding: 18px; border: 1px solid var(--line); border-radius: var(--radius-sm); color: var(--soft); background: var(--panel); text-decoration: none; }
.how-to-grid a:hover { border-color: var(--red); transform: translateY(-1px); }
.how-to-grid b { flex: 0 0 auto; width: 30px; height: 30px; display: grid; place-items: center; border-radius: 50%; color: #2b070e; background: var(--red); font-family: var(--mono); }
.how-to-grid span, .how-to-grid strong { display: block; }
.how-to-grid strong { margin-bottom: 5px; color: var(--text); line-height: 1.2; }
.how-to-grid span { font-size: 0.84rem; }

.tool-layout { display: grid; grid-template-columns: minmax(0, 1.1fr) minmax(330px, 0.9fr); gap: 18px; align-items: start; }
.tool-panel, .result-panel, .scenario-panel, .timeline-panel, .monitor-card, .training-shell { border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel); box-shadow: var(--shadow); }
.tool-panel { padding: 24px; }
fieldset { margin: 0 0 18px; padding: 0; border: 0; }
legend { width: 100%; margin-bottom: 8px; padding-bottom: 8px; border-bottom: 1px solid var(--line); color: var(--red); font-weight: 900; }
.check-row { display: flex; gap: 10px; align-items: flex-start; padding: 9px 10px; border-radius: 10px; color: var(--soft); cursor: pointer; }
.check-row:hover { background: var(--panel-2); }
.check-row.critical { color: var(--red); }
input[type="checkbox"] { flex: 0 0 auto; width: 19px; height: 19px; margin-top: 2px; accent-color: var(--red-dark); }
.form-actions { display: flex; gap: 8px; flex-wrap: wrap; }
.result-panel { position: sticky; top: 112px; min-height: 280px; padding: 28px; border-color: var(--line-strong); }
.result-panel[data-level="critical"] { border-color: var(--red); background: linear-gradient(145deg, var(--danger-soft), var(--panel)); }
.result-panel[data-level="urgent"] { border-color: var(--amber); }
.result-panel[data-level="watch"] { border-color: var(--cyan); }
.result-state { display: inline-flex; padding: 5px 9px; border: 1px solid var(--line-strong); border-radius: 999px; color: var(--red); font: 800 0.7rem/1 var(--mono); text-transform: uppercase; letter-spacing: 0.06em; }
.result-panel h3 { margin: 18px 0 10px; font-size: 1.65rem; }
.result-panel ol, .result-panel ul { padding-left: 21px; }
.result-panel li + li { margin-top: 7px; }
.result-alert { margin-top: 18px; padding: 13px; border-left: 4px solid var(--red); background: var(--danger-soft); }

.evidence-legend { display: grid; grid-template-columns: auto 1fr auto 1fr; gap: 10px 12px; align-items: center; margin-top: 22px; padding: 18px; border: 1px solid var(--line); border-radius: var(--radius-sm); background: var(--panel); }
.evidence-legend p { margin: 0; color: var(--muted); font-size: 0.82rem; }
.evidence-tag { width: max-content; display: inline-flex; padding: 5px 8px; border: 1px solid currentColor; border-radius: 999px; font: 850 0.68rem/1 var(--mono); letter-spacing: 0.05em; text-transform: uppercase; }
.evidence-tag.guideline { color: var(--green); }
.evidence-tag.evidence { color: var(--cyan); }
.evidence-tag.individual { color: var(--violet); }
.evidence-tag.local { color: var(--amber); }

.scenario-tabs, .timeline-tabs, .training-nav { display: flex; gap: 8px; flex-wrap: wrap; margin-bottom: 14px; }
.scenario-tabs button, .timeline-tabs button, .training-tab { padding: 10px 14px; border: 1px solid var(--line); border-radius: 999px; color: var(--soft); background: var(--panel); font-weight: 850; cursor: pointer; }
.scenario-tabs button.active, .timeline-tabs button.active, .training-tab.active { color: #2b070e; border-color: var(--red); background: var(--red); }
.scenario-panel, .timeline-panel { padding: 30px; }
.scenario-panel h3, .timeline-panel h3 { margin: 12px 0 8px; font-size: 1.7rem; }
.scenario-panel ul, .timeline-panel ul { padding-left: 21px; }
.scenario-panel li + li, .timeline-panel li + li { margin-top: 8px; }
.time-badge { color: var(--red); font: 900 0.78rem/1 var(--mono); text-transform: uppercase; letter-spacing: 0.08em; }
.never-line { margin-top: 20px; padding: 13px 15px; border-left: 4px solid var(--red); background: var(--danger-soft); }

.biomarker-grid, .syntax-caveats { display: grid; grid-template-columns: repeat(3, 1fr); gap: 14px; margin-top: 22px; }
.info-card, .syntax-caveats article, .syntax-summary article, .complication-card { padding: 22px; border: 1px solid var(--line); border-radius: var(--radius-sm); background: var(--panel); }
.info-card h3, .syntax-caveats h3 { margin: 15px 0 8px; }
.info-card p, .syntax-caveats p { margin-bottom: 0; color: var(--soft); }
.danger-card { border-color: rgba(255, 102, 122, 0.55); background: linear-gradient(145deg, var(--danger-soft), var(--panel)); }
.compact-form > fieldset > label:not(.check-row) { display: block; color: var(--soft); font-weight: 750; }
select { width: 100%; min-height: 46px; margin-top: 7px; padding: 10px 12px; border: 1px solid var(--line-strong); border-radius: 10px; color: var(--text); background: var(--bg); }
.warning-box { margin-top: 18px; padding: 15px 17px; border: 1px solid rgba(255, 102, 122, 0.5); border-radius: var(--radius-sm); background: var(--danger-soft); }

.monitor-card { display: grid; grid-template-columns: 1fr 1fr; margin-top: 22px; overflow: hidden; }
.monitor-card > div { padding: 26px; }
.monitor-card > div + div { border-left: 1px solid var(--line); }
.monitor-card h3 { margin: 14px 0 8px; }
.monitor-card p { margin-bottom: 0; color: var(--soft); }
.complications-heading { margin-top: 70px; }
.complication-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: 14px; }
.complication-card { width: 100%; color: var(--text); text-align: left; cursor: pointer; }
.complication-card:hover, .complication-card[aria-expanded="true"] { border-color: var(--red); }
.complication-card header { display: flex; justify-content: space-between; gap: 12px; align-items: center; }
.complication-card h3 { margin: 0; font-size: 1.08rem; }
.complication-card .signal { color: var(--red); font: 850 0.7rem/1 var(--mono); text-transform: uppercase; }
.complication-detail { display: none; margin: 14px 0 0; padding-top: 14px; border-top: 1px solid var(--line); color: var(--soft); }
.complication-card[aria-expanded="true"] .complication-detail { display: block; }

.syntax-summary { display: grid; grid-template-columns: repeat(3, 1fr); gap: 14px; margin-bottom: 22px; }
.syntax-summary b, .syntax-summary span { display: block; }
.syntax-summary b { color: var(--red); }
.syntax-summary span { margin-top: 8px; color: var(--soft); }
.syntax-tool { margin-top: 20px; }

.training-shell { padding: 28px; }
.progress-track { height: 8px; margin-bottom: 25px; overflow: hidden; border-radius: 999px; background: var(--bg); }
.progress-track progress { display: block; width: 100%; height: 100%; border: 0; background: transparent; appearance: none; }
.progress-track progress::-webkit-progress-bar { background: var(--bg); }
.progress-track progress::-webkit-progress-value { background: linear-gradient(90deg, var(--red), var(--violet)); }
.progress-track progress::-moz-progress-bar { background: var(--red); }
.training-meta { display: flex; justify-content: space-between; gap: 12px; margin-bottom: 13px; color: var(--muted); font: 800 0.72rem/1.2 var(--mono); text-transform: uppercase; }
.training-shell h3 { font-size: 1.65rem; }
.case-stem { padding: 17px; border-left: 4px solid var(--red); background: var(--panel-2); }
.answer-list { display: grid; gap: 9px; margin-top: 18px; }
.answer-option { width: 100%; padding: 13px 15px; border: 1px solid var(--line); border-radius: 12px; color: var(--text); background: var(--bg); text-align: left; cursor: pointer; }
.answer-option:hover { border-color: var(--red); }
.answer-option.correct { border-color: var(--green); background: rgba(103, 222, 178, 0.12); }
.answer-option.incorrect { border-color: var(--red); background: var(--danger-soft); }
.option-feedback { display: none; margin: -3px 0 6px; padding: 11px 13px; border-radius: 10px; color: var(--soft); background: var(--panel-2); }
.option-feedback.visible { display: block; }
.pearl { margin-top: 17px; padding: 13px; border-left: 4px solid var(--amber); background: rgba(255, 199, 90, 0.08); }
.training-actions { display: flex; gap: 8px; flex-wrap: wrap; margin-top: 22px; }
.flashcard { width: 100%; min-height: 270px; display: grid; place-items: center; padding: 30px; border: 1px solid var(--line-strong); border-radius: var(--radius); color: var(--text); background: linear-gradient(145deg, var(--panel-2), var(--panel)); text-align: center; cursor: pointer; }
.flashcard span { color: var(--red); font: 800 0.72rem/1 var(--mono); text-transform: uppercase; letter-spacing: 0.08em; }
.flashcard h3 { max-width: 760px; margin: 18px 0 0; font-size: clamp(1.6rem, 4vw, 2.5rem); }
.flashcard.revealed h3 { color: var(--green); }

.references-list { display: grid; gap: 10px; }
.reference-card { display: grid; grid-template-columns: 76px minmax(0, 1fr) auto; gap: 16px; align-items: center; padding: 17px; border: 1px solid var(--line); border-radius: 14px; background: var(--panel); }
.reference-year { color: var(--red); font: 900 1rem/1 var(--mono); }
.reference-card h3 { margin: 0 0 4px; font-size: 1rem; }
.reference-card p { margin: 0; color: var(--muted); font-size: 0.82rem; }
.reference-card a { color: var(--red); font-weight: 850; white-space: nowrap; }

footer { padding: 48px 0; border-top: 1px solid var(--line); background: var(--bg-soft); }
.footer-grid { display: grid; grid-template-columns: 1fr auto; gap: 28px; }
.footer-grid p { max-width: 700px; color: var(--muted); }
.footer-grid > div:last-child { display: grid; gap: 7px; align-content: start; }
.footer-grid a { color: var(--red); font-weight: 750; }

@media (max-width: 980px) {
  .nav-shell { align-items: flex-start; padding-block: 12px; }
  .nav-links a { display: none; }
  .hero-grid, .tool-layout { grid-template-columns: 1fr; }
  .how-to-grid { grid-template-columns: repeat(2, minmax(0, 1fr)); }
  .result-panel { position: static; }
  .safety-grid { grid-template-columns: 1fr 1fr; }
  .safety-grid div:nth-child(2) { border-right: 0; }
  .safety-grid div:nth-child(-n+2) { border-bottom: 1px solid var(--line); }
  .biomarker-grid, .complication-grid, .syntax-summary, .syntax-caveats { grid-template-columns: 1fr 1fr; }
}

@media (max-width: 720px) {
  .wrap { width: min(100% - 22px, var(--max)); }
  .official-strip .wrap, .section-heading { display: block; }
  .official-strip span { display: block; margin-top: 3px; }
  .hero { padding-top: 52px; }
  h1 { font-size: clamp(2.55rem, 14vw, 4.5rem); }
  .section { padding: 64px 0; }
  .section-heading > p { margin-top: 16px; }
  .safety-grid, .how-to-grid, .biomarker-grid, .complication-grid, .syntax-summary, .syntax-caveats, .monitor-card, .footer-grid { grid-template-columns: 1fr; }
  .safety-grid div { border-right: 0; border-bottom: 1px solid var(--line); }
  .safety-grid div:last-child { border-bottom: 0; }
  .monitor-card > div + div { border-left: 0; border-top: 1px solid var(--line); }
  .evidence-legend { grid-template-columns: auto 1fr; }
  .reference-card { grid-template-columns: 58px minmax(0, 1fr); }
  .reference-card a { grid-column: 2; }
  .brand small { display: none; }
  .control-button { padding: 8px; font-size: 0.75rem; }
}

@media (prefers-reduced-motion: reduce) {
  *, *::before, *::after { scroll-behavior: auto !important; transition: none !important; animation: none !important; }
}

@media print {
  :root, html[data-theme="light"], html[data-theme="dark"], html.a11y-contrast {
    color-scheme: light;
    --bg: #ffffff;
    --bg-soft: #ffffff;
    --panel: #ffffff;
    --panel-2: #fff3f2;
    --text: #301419;
    --soft: #5f353a;
    --muted: #79555a;
    --line: #d1a7aa;
    --line-strong: #a9757b;
    --red: #a71934;
    --amber: #704600;
    --shadow: none;
  }
  body, .hero, .section, .section-tint, .safety-band { color: var(--text) !important; background: #ffffff !important; }
  .topbar, .official-strip, .hero-actions, .nav-links, .training-actions, .training-nav, .scenario-tabs, .timeline-tabs, footer { display: none !important; }
  .section { padding: 28px 0; break-before: auto; }
  .tool-layout, .biomarker-grid, .complication-grid, .syntax-summary, .syntax-caveats, .monitor-card { grid-template-columns: 1fr; }
  .result-panel, .tool-panel, .scenario-panel, .timeline-panel, .monitor-card, .training-shell, .info-card, .syntax-summary article, .syntax-caveats article, .complication-card { box-shadow: none; break-inside: avoid; }
  .result-panel { position: static; }
  .complication-detail { display: block; }
  a[href]::after { content: none; }
}