:root {
  color-scheme: dark;
  --bg: #0b0608;
  --bg-soft: #160b0f;
  --panel: #1d1014;
  --panel-2: #29151b;
  --text: #fff8f7;
  --soft: #ebd2d2;
  --muted: #b9989d;
  --line: rgba(255, 224, 221, 0.15);
  --line-strong: rgba(255, 224, 221, 0.3);
  --red: #ff6675;
  --red-dark: #c62a43;
  --red-soft: rgba(255, 102, 117, 0.12);
  --amber: #ffca67;
  --amber-soft: rgba(255, 202, 103, 0.1);
  --green: #58e6b1;
  --green-soft: rgba(88, 230, 177, 0.1);
  --cyan: #65d9f2;
  --violet: #c3a6ff;
  --shadow: 0 24px 72px rgba(0, 0, 0, 0.36);
  --radius: 22px;
  --radius-sm: 14px;
  --max: 1220px;
  --sans: Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;
  --mono: ui-monospace, SFMono-Regular, Menlo, Monaco, Consolas, monospace;
}

html[data-theme="light"] {
  color-scheme: light;
  --bg: #ffffff;
  --bg-soft: #fff5f5;
  --panel: #ffffff;
  --panel-2: #f8e9eb;
  --text: #32171d;
  --soft: #563139;
  --muted: #74535a;
  --line: #c7a8ae;
  --line-strong: #98737b;
  --red: #b4233f;
  --red-dark: #8f1831;
  --red-soft: #fff0f2;
  --amber: #805300;
  --amber-soft: #fff8e8;
  --green: #087857;
  --green-soft: #eaf9f3;
  --cyan: #006a7d;
  --violet: #6246b5;
  --shadow: 0 18px 50px rgba(80, 26, 37, 0.11);
}

html.a11y-contrast {
  color-scheme: dark;
  --bg: #000000;
  --bg-soft: #000000;
  --panel: #000000;
  --panel-2: #111111;
  --text: #ffffff;
  --soft: #ffffff;
  --muted: #ffffff;
  --line: #ffffff;
  --line-strong: #ffffff;
  --red: #ffea00;
  --red-dark: #ffea00;
  --red-soft: #000000;
  --amber: #ffea00;
  --amber-soft: #000000;
  --green: #72ffb2;
  --green-soft: #000000;
  --cyan: #7eeeff;
  --violet: #dccaff;
  --shadow: none;
}

* { box-sizing: border-box; }
html { scroll-behavior: smooth; scroll-padding-top: 116px; }
body {
  margin: 0;
  min-width: 320px;
  color: var(--text);
  background:
    radial-gradient(circle at 6% 0, rgba(255, 102, 117, 0.15), transparent 30rem),
    radial-gradient(circle at 95% 16%, rgba(101, 217, 242, 0.08), transparent 28rem),
    var(--bg);
  font: 400 1rem/1.58 var(--sans);
}
body.focus-mode.focus-has-target .section:not(:target),
body.focus-mode .command-band,
body.focus-mode footer { opacity: 0.34; }
body.focus-mode .section:target { opacity: 1; }
button, input, select { font: inherit; }
button, a, input, select, [tabindex] { -webkit-tap-highlight-color: transparent; }
a { color: inherit; }
:where(button, a, input, select, [tabindex]):focus-visible { outline: 3px solid var(--amber); outline-offset: 3px; }
.wrap { width: min(var(--max), calc(100% - 32px)); margin-inline: auto; }
.skip-link { position: fixed; z-index: 200; top: -80px; left: 14px; padding: 10px 15px; border-radius: 10px; color: var(--bg); background: var(--text); font-weight: 900; }
.skip-link:focus { top: 12px; }
.sr-only { position: absolute !important; width: 1px !important; height: 1px !important; padding: 0 !important; margin: -1px !important; overflow: hidden !important; clip: rect(0, 0, 0, 0) !important; white-space: nowrap !important; border: 0 !important; }
.noscript-warning { padding: 13px 18px; color: #ffffff; background: #8f1831; text-align: center; }

.topbar { position: sticky; z-index: 60; top: 0; border-bottom: 1px solid var(--line); background: rgba(11, 6, 8, 0.92); backdrop-filter: blur(18px); }
html[data-theme="light"] .topbar { background: rgba(255, 255, 255, 0.95); }
.nav-shell { min-height: 76px; display: flex; align-items: center; justify-content: space-between; gap: 20px; }
.brand { min-width: max-content; display: flex; align-items: center; gap: 11px; text-decoration: none; }
.brand-mark { width: 46px; height: 46px; display: grid; place-items: center; border: 1px solid var(--line-strong); border-radius: 15px; background: var(--panel-2); font-size: 1.35rem; }
.brand strong, .brand small { display: block; }
.brand small { margin-top: 2px; color: var(--muted); font: 0.66rem/1.2 var(--mono); letter-spacing: 0.08em; text-transform: uppercase; }
.nav-links { display: flex; justify-content: flex-end; align-items: center; gap: 4px; flex-wrap: wrap; }
.nav-links a, .control-button, .menu-button { min-height: 44px; padding: 8px 10px; border: 1px solid transparent; border-radius: 10px; color: var(--soft); background: transparent; text-decoration: none; font-size: 0.8rem; font-weight: 800; cursor: pointer; }
.nav-links a:hover, .control-button:hover, .control-button[aria-pressed="true"], .menu-button:hover { color: var(--text); border-color: var(--line-strong); background: var(--panel-2); }
.menu-button { display: none; }
.review-strip { padding: 8px 0; color: #27070d; background: var(--amber); }
.review-strip .wrap { display: flex; justify-content: space-between; gap: 18px; font-size: 0.78rem; }
.review-strip strong { text-transform: uppercase; letter-spacing: 0.06em; }
html[data-theme="light"] .review-strip { color: #ffffff; background: #805300; }

/* Revista clínica: imagens e ACRA são aprimoramentos progressivos. */
.acra-mode-dock { position: sticky; z-index: 45; top: 76px; border-bottom: 1px solid var(--line); background: var(--bg); background: color-mix(in srgb, var(--bg) 94%, transparent); backdrop-filter: blur(16px); }
.acra-mode-dock__inner { min-height: 72px; display: grid; grid-template-columns: minmax(220px, 0.72fr) auto minmax(280px, 1fr); gap: 18px; align-items: center; padding-block: 10px; }
.acra-mode-dock__inner > div:first-child strong { display: block; margin-top: 3px; line-height: 1.2; }
.acra-mode-buttons { display: flex; gap: 6px; flex-wrap: wrap; }
.acra-mode-buttons button { min-height: 44px; padding: 8px 12px; border: 1px solid var(--line-strong); border-radius: 999px; color: var(--soft); background: var(--panel); font-weight: 900; cursor: pointer; }
.acra-mode-buttons button:hover { border-color: var(--red); color: var(--text); }
.acra-mode-buttons button[aria-pressed="true"] { color: #27070d; border-color: var(--amber); background: var(--amber); }
html[data-theme="light"] .acra-mode-buttons button[aria-pressed="true"] { color: #ffffff; background: #805300; }
.acra-mode-status { margin: 0; color: var(--muted); font-size: 0.76rem; line-height: 1.35; }
.acra-mode-status strong { color: var(--amber); }

.visual-grid { display: grid; grid-template-columns: minmax(0, 1fr); gap: 42px; margin-block: 38px; align-items: start; }
.visual-grid--2, .visual-grid--3 { grid-template-columns: minmax(0, 1fr); }
.hero-visual-grid { margin-top: 42px; margin-bottom: 0; }
.clinical-visual { width: 100%; min-width: 0; margin: 42px 0; overflow: hidden; border: 1px solid var(--line-strong); border-radius: var(--radius); background: var(--panel); box-shadow: var(--shadow); }
.visual-grid > .clinical-visual { margin: 0; }
.visual-frame { position: relative; min-width: 0; overflow: hidden; border-bottom: 1px solid var(--line); background: #07090d; }
.visual-frame picture { display: block; aspect-ratio: 1672 / 941; }
.visual-frame img { width: 100%; height: auto; aspect-ratio: 1672 / 941; display: block; object-fit: contain; background: #07090d; }
.visual-zoom { display: none; position: absolute; right: 12px; bottom: 12px; min-height: 44px; padding: 8px 12px; border: 1px solid rgba(255, 255, 255, 0.72); border-radius: 11px; color: #ffffff; background: rgba(7, 9, 13, 0.9); box-shadow: 0 5px 24px rgba(0, 0, 0, 0.35); font-weight: 900; cursor: pointer; }
.visual-zoom:hover { border-color: var(--amber); background: #000000; }
.clinical-visual figcaption { display: grid; gap: 12px; padding: 24px 28px 28px; color: var(--soft); font-size: 0.96rem; }
.clinical-visual figcaption > strong { color: var(--text); font-size: clamp(1.08rem, 2vw, 1.34rem); line-height: 1.25; }
.clinical-visual figcaption > span { display: block; }
.visual-source { color: var(--muted); font: 750 0.78rem/1.5 var(--mono); }
.visual-source a, .visual-full-link, .visual-download { color: var(--red); font-weight: 850; }
.visual-source a { display: inline; overflow-wrap: anywhere; }
.visual-description { padding: 14px 16px; border: 1px solid var(--line); border-radius: 12px; background: var(--panel-2); }
.visual-description summary { color: var(--text); font-weight: 850; cursor: default; }
.visual-description p { margin: 9px 0 0; color: var(--soft); }
.visual-actions { display: flex; gap: 10px; align-items: center; flex-wrap: wrap; }
.visual-full-link, .visual-download { width: fit-content; min-height: 44px; display: inline-flex; align-items: center; padding: 9px 13px; border: 1px solid var(--line-strong); border-radius: 11px; background: var(--panel-2); text-decoration: none; }
.visual-full-link:hover, .visual-download:hover { color: var(--text); border-color: var(--red); }
.visual-disclosure { padding: 9px 12px; border-left: 4px solid var(--cyan); color: var(--muted); background: rgba(101, 217, 242, 0.07); font-size: 0.8rem; }

.acra-slot-grid { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 16px; margin-top: 24px; }
.acra-slot { min-width: 0; display: grid; grid-template-columns: minmax(0, 1fr) auto; gap: 20px; align-items: center; margin-top: 24px; padding: 22px; border: 1px solid var(--line-strong); border-left: 5px solid var(--violet); border-radius: var(--radius); background: var(--panel); background: linear-gradient(135deg, color-mix(in srgb, var(--violet) 9%, transparent), var(--panel)); }
.acra-slot-grid .acra-slot { grid-template-columns: minmax(0, 1fr); margin-top: 0; }
.acra-kicker { color: var(--violet); font: 850 0.7rem/1.2 var(--mono); letter-spacing: 0.07em; text-transform: uppercase; }
.acra-slot h3 { margin: 8px 0; font-size: 1.35rem; }
.acra-slot p { margin: 0; color: var(--soft); }
.acra-slot__copy, .acra-slot__actions { min-width: 0; max-width: 100%; }
.acra-slot__actions { min-width: 190px; display: grid; gap: 9px; justify-items: start; }
.acra-slot__actions [data-acra-status] { color: var(--muted); font-size: 0.73rem; line-height: 1.35; }
body[data-acra-mode="off"] .acra-slot__actions { display: none; }

/* Runtime ACRA local: leitura em camadas, DOM seguro e largura sempre contida. */
.acra-slot > .acra-runtime { grid-column: 1 / -1; }
.acra-runtime,
.acra-runtime *,
.acra-runtime *::before,
.acra-runtime *::after { min-width: 0; box-sizing: border-box; }
.acra-runtime {
  width: 100%;
  max-width: 100%;
  display: grid;
  grid-template-columns: minmax(0, 1fr);
  gap: 16px;
  margin-top: 18px;
  padding: clamp(15px, 2.4vw, 24px);
  border: 1px solid color-mix(in srgb, var(--violet) 55%, var(--line));
  border-radius: 18px;
  background: linear-gradient(145deg, color-mix(in srgb, var(--violet) 7%, var(--panel)), var(--panel));
  color: var(--text);
  overflow-wrap: anywhere;
  word-break: normal;
}
.acra-runtime__header { display: grid; grid-template-columns: minmax(0, 1fr); gap: 8px; padding-bottom: 15px; border-bottom: 1px solid var(--line); }
.acra-runtime__badge { width: fit-content; max-width: 100%; margin: 0; padding: 6px 9px; border: 1px solid var(--line-strong); border-radius: 999px; color: var(--violet) !important; background: color-mix(in srgb, var(--violet) 10%, var(--panel)); font: 850 0.68rem/1.25 var(--mono); letter-spacing: 0.045em; text-transform: uppercase; }
.acra-runtime__artifact-title { margin: 0; color: var(--text); font-size: clamp(1.35rem, 4vw, 2rem); line-height: 1.08; letter-spacing: -0.025em; }
.acra-runtime__subtitle { margin: 0 !important; color: var(--amber) !important; font-weight: 800; line-height: 1.4; }
.acra-runtime__summary, .acra-runtime__copy { margin: 0 !important; color: var(--soft) !important; line-height: 1.58; }
.acra-runtime__critical,
.acra-runtime__components,
.acra-runtime__cards,
.acra-runtime__quiz,
.acra-runtime__actions { min-width: 0; display: grid; grid-template-columns: minmax(0, 1fr); gap: 12px; }
.acra-runtime__critical { grid-template-columns: repeat(auto-fit, minmax(min(100%, 16rem), 1fr)); }
.acra-runtime__critical-item,
.acra-runtime__component,
.acra-runtime__card,
.acra-runtime__question {
  min-width: 0;
  max-width: 100%;
  padding: 15px;
  border: 1px solid var(--line);
  border-radius: 13px;
  background: color-mix(in srgb, var(--panel-2) 76%, var(--panel));
}
.acra-runtime__critical-item { border-left-width: 5px; }
.acra-runtime__critical-item[data-severity="danger"] { border-left-color: var(--red); background: var(--red-soft); }
.acra-runtime__critical-item[data-severity="warning"] { border-left-color: var(--amber); background: var(--amber-soft); }
.acra-runtime__critical-item[data-severity="info"] { border-left-color: var(--cyan); }
.acra-runtime__critical-item h4,
.acra-runtime__title,
.acra-runtime__item-title { margin: 0 0 7px; color: var(--text); line-height: 1.25; }
.acra-runtime__title { color: var(--violet); font-size: 1.05rem; }
.acra-runtime__cards { grid-template-columns: repeat(auto-fit, minmax(min(100%, 15rem), 1fr)); }
.acra-runtime__card[data-tone="danger"], .acra-runtime__component[data-tone="danger"] { border-left: 4px solid var(--red); }
.acra-runtime__card[data-tone="warning"], .acra-runtime__component[data-tone="warning"] { border-left: 4px solid var(--amber); }
.acra-runtime__card[data-tone="success"], .acra-runtime__component[data-tone="success"] { border-left: 4px solid var(--green); }
.acra-runtime__card[data-tone="info"], .acra-runtime__component[data-tone="info"] { border-left: 4px solid var(--cyan); }
.acra-runtime__list,
.acra-runtime__steps,
.acra-runtime__checklist,
.acra-runtime__sources { max-width: 100%; margin: 10px 0 0; padding-left: 1.25rem; color: var(--soft); }
.acra-runtime__list li + li,
.acra-runtime__steps li + li,
.acra-runtime__checklist li + li,
.acra-runtime__sources li + li { margin-top: 7px; }
.acra-runtime__step strong { display: block; margin-bottom: 5px; color: var(--text); }
.acra-runtime__key-values { min-width: 0; display: grid; grid-template-columns: repeat(auto-fit, minmax(min(100%, 13rem), 1fr)); gap: 9px; margin: 10px 0 0; }
.acra-runtime__key-value { min-width: 0; padding: 11px; border: 1px solid var(--line); border-radius: 10px; background: var(--panel); }
.acra-runtime__key-value dt { color: var(--red); font-weight: 850; }
.acra-runtime__key-value dd { margin: 4px 0 0; color: var(--soft); }
.acra-runtime__tabs { min-width: 0; max-width: 100%; display: flex; gap: 7px; margin: 10px 0; padding: 2px 2px 7px; overflow-x: auto; overscroll-behavior-inline: contain; scrollbar-gutter: stable; }
.acra-runtime__tab,
.acra-runtime__accordion-trigger,
.acra-runtime__submit,
.acra-runtime__action {
  min-height: 44px;
  max-width: 100%;
  padding: 9px 12px;
  border: 1px solid var(--line-strong);
  border-radius: 10px;
  color: var(--text);
  background: var(--panel);
  font: 800 0.86rem/1.35 var(--sans);
  white-space: normal;
  overflow-wrap: anywhere;
  cursor: pointer;
}
.acra-runtime__tab { flex: 0 0 auto; max-width: min(18rem, 80vw); }
.acra-runtime__tab[aria-selected="true"],
.acra-runtime__submit:hover,
.acra-runtime__action:hover,
.acra-runtime__accordion-trigger:hover { border-color: var(--violet); background: color-mix(in srgb, var(--violet) 12%, var(--panel)); }
.acra-runtime__accordion { min-width: 0; display: grid; gap: 8px; }
.acra-runtime__accordion-item { min-width: 0; max-width: 100%; }
.acra-runtime__accordion-trigger { width: 100%; text-align: left; }
.acra-runtime__panel { min-width: 0; max-width: 100%; margin-top: 8px; padding: 12px; border: 1px solid var(--line); border-radius: 10px; background: var(--panel); }
.acra-runtime__table-scroll {
  width: 100%;
  min-width: 0;
  max-width: 100%;
  margin-top: 10px;
  border: 1px solid var(--line);
  border-radius: 11px;
  overflow-x: auto;
  overflow-y: visible;
  overscroll-behavior-inline: contain;
  scrollbar-gutter: stable;
  -webkit-overflow-scrolling: touch;
}
.acra-runtime__table { width: 100%; min-width: 42rem; max-width: none; margin: 0; table-layout: auto; font-size: 0.8rem; }
.acra-runtime__table th, .acra-runtime__table td { min-width: 0; padding: 11px; overflow-wrap: anywhere; }
.acra-runtime__checklist { display: grid; gap: 7px; padding-left: 0; list-style: none; }
.acra-runtime__check-item { min-width: 0; display: grid; grid-template-columns: auto minmax(0, 1fr); gap: 9px; align-items: start; padding: 9px; border-radius: 10px; background: var(--panel); }
.acra-runtime__check-item label, .acra-runtime__check-item strong, .acra-runtime__check-item small { min-width: 0; max-width: 100%; display: block; overflow-wrap: anywhere; }
.acra-runtime__check-item small { margin-top: 4px; color: var(--muted); }
.acra-runtime__options { min-width: 0; display: grid; grid-template-columns: minmax(0, 1fr); gap: 7px; margin-top: 9px; }
.acra-runtime fieldset { min-width: 0; max-width: 100%; margin: 0; padding: 0; border: 0; }
.acra-runtime legend { max-width: 100%; padding: 0; color: var(--text); overflow-wrap: anywhere; }
.acra-runtime__option { min-width: 0; max-width: 100%; display: grid; grid-template-columns: auto minmax(0, 1fr); gap: 8px; align-items: start; padding: 9px; border: 1px solid var(--line); border-radius: 9px; color: var(--soft); background: var(--panel); overflow-wrap: anywhere; }
.acra-runtime__submit { margin-top: 10px; }
.acra-runtime__submit:disabled { cursor: not-allowed; opacity: 0.55; }
.acra-runtime__feedback, .acra-runtime__action-preview { min-width: 0; max-width: 100%; margin: 10px 0 0 !important; padding: 11px; border-left: 4px solid var(--amber); border-radius: 8px; color: var(--soft) !important; background: var(--amber-soft); overflow-wrap: anywhere; }
.acra-runtime__feedback[data-correct="true"] { border-left-color: var(--green); background: var(--green-soft); }
.acra-runtime__feedback[data-correct="false"] { border-left-color: var(--red); background: var(--red-soft); }
.acra-runtime__progress { min-width: 0; display: grid; gap: 7px; }
.acra-runtime__progress-track { width: 100%; min-width: 0; height: 12px; overflow: hidden; border: 1px solid var(--line-strong); border-radius: 999px; background: var(--bg); }
.acra-runtime__progress-value { width: 0; height: 100%; border-radius: inherit; background: linear-gradient(90deg, var(--violet), var(--cyan)); transition: width 180ms ease; }
.acra-runtime__progress-copy { color: var(--muted); font: 800 0.76rem/1.3 var(--mono); }
.acra-runtime__sources a { color: var(--red); overflow-wrap: anywhere; word-break: break-word; }
.acra-runtime__sources small { display: block; margin-top: 3px; color: var(--muted); }
.acra-runtime__actions { grid-template-columns: repeat(auto-fit, minmax(min(100%, 13rem), 1fr)); }
.acra-runtime__action { width: 100%; text-align: left; }

dialog { padding: 0; border: 1px solid var(--line-strong); border-radius: var(--radius); color: var(--text); background: var(--panel); box-shadow: 0 30px 100px rgba(0, 0, 0, 0.7); }
dialog::backdrop { background: rgba(4, 2, 3, 0.86); backdrop-filter: blur(5px); }
.visual-dialog { width: min(1480px, calc(100% - 28px)); max-height: calc(100dvh - 28px); }
.acra-stage { width: min(1120px, calc(100% - 28px)); max-height: calc(100dvh - 28px); }
.dialog-shell { max-height: calc(100dvh - 30px); padding: 22px; overflow: auto; overscroll-behavior: contain; }
.dialog-toolbar { position: sticky; z-index: 2; top: -22px; display: flex; justify-content: space-between; gap: 16px; align-items: center; margin: -22px -22px 18px; padding: 13px 18px; border-bottom: 1px solid var(--line); background: var(--panel); background: color-mix(in srgb, var(--panel) 95%, transparent); backdrop-filter: blur(14px); }
.dialog-close { min-height: 44px; padding: 8px 12px; border: 1px solid var(--line-strong); border-radius: 10px; color: var(--text); background: var(--panel-2); font-weight: 900; cursor: pointer; }
.visual-dialog h2, .acra-stage h2 { margin-bottom: 10px; font-size: clamp(1.65rem, 4vw, 2.5rem); }
.visual-dialog p { color: var(--soft); }
.visual-dialog img { width: 100%; height: auto; display: block; margin-top: 16px; border: 1px solid var(--line); border-radius: 14px; background: #07090d; }
.acra-stage__shell { min-width: 0; max-width: 100%; min-height: 0; }
[data-acra-stage-content] { width: 100%; min-width: 0; max-width: 100%; }
.acra-stage__footer { display: flex; justify-content: space-between; gap: 14px; align-items: center; margin-top: 22px; padding-top: 16px; border-top: 1px solid var(--line); color: var(--muted); font-size: 0.8rem; }
[hidden] { display: none !important; }

.hero { padding: 76px 0 62px; }
.hero-grid { display: grid; grid-template-columns: minmax(0, 1.25fr) minmax(340px, 0.75fr); gap: 42px; align-items: center; }
.eyebrow { display: inline-block; color: var(--red); font: 850 0.73rem/1.2 var(--mono); letter-spacing: 0.1em; text-transform: uppercase; }
h1, h2, h3, p { margin-top: 0; }
h1 { max-width: 820px; margin: 10px 0 22px; font-size: clamp(3.2rem, 8vw, 7rem); line-height: 0.92; letter-spacing: -0.065em; }
h1 em { color: var(--red); font-style: normal; }
h2 { margin-bottom: 0; font-size: clamp(2rem, 4.4vw, 3.55rem); line-height: 1.04; letter-spacing: -0.047em; }
h3 { line-height: 1.2; letter-spacing: -0.022em; }
.hero-lead { max-width: 750px; color: var(--soft); font-size: 1.18rem; }
.hero-actions, .form-actions, .filter-row, .training-tabs { display: flex; gap: 9px; flex-wrap: wrap; }
.hero-actions { margin: 28px 0 16px; }
.button, .filter-button, .training-tab, .layer-button, .timeline-tabs button, .phenotype-buttons button {
  min-height: 44px;
  display: inline-flex;
  align-items: center;
  justify-content: center;
  padding: 10px 15px;
  border: 1px solid var(--line-strong);
  border-radius: 12px;
  color: var(--text);
  background: var(--panel);
  text-decoration: none;
  font-weight: 850;
  cursor: pointer;
}
.button:hover, .filter-button:hover, .training-tab:hover, .layer-button:hover, .timeline-tabs button:hover, .phenotype-buttons button:hover { transform: translateY(-1px); border-color: var(--red); }
.button.primary { color: #27070d; border-color: var(--red); background: var(--red); }
.button.danger { border-color: var(--red); color: var(--red); background: var(--red-soft); }
.button.ghost { color: var(--muted); background: transparent; }
.microcopy { max-width: 720px; color: var(--muted); font-size: 0.82rem; }
.source-links { margin: 14px 0 0; padding-top: 11px; border-top: 1px solid var(--line); color: var(--muted) !important; font-size: 0.76rem; }
.source-links a { color: var(--red); font-weight: 800; }
html[data-theme="light"] .button.primary,
html[data-theme="light"] .timeline-tabs button.active,
html[data-theme="light"] .phenotype-buttons button.active,
html[data-theme="light"] .layer-button.active,
html[data-theme="light"] .filter-button.active,
html[data-theme="light"] .training-tab.active { color: #ffffff; }

.mortality-card { padding: 27px; border: 1px solid rgba(255, 102, 117, 0.55); border-radius: var(--radius); background: linear-gradient(145deg, var(--red-soft), var(--panel)); box-shadow: var(--shadow); }
.live-label { display: inline-flex; align-items: center; gap: 9px; color: var(--red); font: 850 0.7rem/1 var(--mono); letter-spacing: 0.07em; text-transform: uppercase; }
.pulse-dot { width: 10px; height: 10px; display: inline-block; border-radius: 50%; background: var(--red); box-shadow: 0 0 0 7px rgba(255, 102, 117, 0.1); }
.counter { display: block; margin: 22px 0 6px; color: var(--red); font: 950 clamp(3.3rem, 8vw, 6.5rem)/0.9 var(--mono); letter-spacing: -0.06em; }
.mortality-card h2 { max-width: 420px; font-size: 1.35rem; line-height: 1.18; letter-spacing: -0.02em; }
.counter-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: 8px; margin: 22px 0; }
.counter-grid div { padding: 12px; border: 1px solid var(--line); border-radius: 12px; background: var(--panel-2); }
.counter-grid b, .counter-grid span { display: block; }
.counter-grid b { color: var(--amber); font-family: var(--mono); }
.counter-grid span { margin-top: 3px; color: var(--muted); font-size: 0.72rem; }
.mortality-card p { color: var(--soft); font-size: 0.8rem; }
.mortality-card a { color: var(--red); font-weight: 850; }
.mortality-card .burden-proof { padding: 13px; border-left: 4px solid var(--amber); background: var(--amber-soft); }
.mortality-card .burden-proof a { color: var(--amber); }

.command-band { border-block: 1px solid var(--line); background: var(--bg-soft); }
.command-grid { display: grid; grid-template-columns: repeat(5, 1fr); }
.command-grid div { padding: 20px; border-right: 1px solid var(--line); }
.command-grid div:last-child { border-right: 0; }
.command-grid b, .command-grid span { display: block; }
.command-grid b { color: var(--red); }
.command-grid span { margin-top: 6px; color: var(--soft); font-size: 0.82rem; }

.section { padding: 84px 0; scroll-margin-top: 112px; }
.section-soft { border-block: 1px solid var(--line); background: var(--bg-soft); }
.section-heading { display: flex; justify-content: space-between; align-items: end; gap: 34px; margin-bottom: 34px; }
.section-heading > p { max-width: 560px; margin-bottom: 2px; color: var(--soft); }
.how-grid { display: grid; grid-template-columns: repeat(5, minmax(0, 1fr)); gap: 11px; margin: 0; padding: 0; list-style: none; }
.how-grid a { height: 100%; display: flex; gap: 11px; padding: 17px; border: 1px solid var(--line); border-radius: var(--radius-sm); color: var(--soft); background: var(--panel); text-decoration: none; }
.how-grid a:hover { border-color: var(--red); transform: translateY(-1px); }
.how-grid b { flex: 0 0 auto; width: 30px; height: 30px; display: grid; place-items: center; border-radius: 50%; color: #27070d; background: var(--red); font-family: var(--mono); }
.how-grid span, .how-grid strong { display: block; }
.how-grid strong { margin-bottom: 5px; color: var(--text); line-height: 1.2; }
.how-grid span { font-size: 0.83rem; }

.pathway-universe { padding: 28px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel); box-shadow: var(--shadow); text-align: center; }
.source-cloud {
  width: min(940px, 100%);
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 10px;
  margin-inline: auto;
}
.source-cloud span {
  min-height: 46px;
  display: flex;
  align-items: center;
  justify-content: center;
  padding: 9px 12px;
  border: 1px solid var(--line);
  border-radius: 13px;
  color: var(--soft);
  background: var(--panel-2);
  font-size: 0.82rem;
  font-weight: 750;
  text-align: center;
}
.flow-arrow { margin: 9px 0; color: var(--red); font-size: 1.35rem; }
.flow-stage { padding: 15px; border: 1px solid var(--line-strong); border-radius: 13px; }
.flow-stage.infection { border-color: var(--amber); background: var(--amber-soft); }
.flow-stage.dysregulation { border-color: var(--red); background: var(--red-soft); }
.flow-stage.recover { border-color: var(--green); background: var(--green-soft); }
.flow-stage.collapse { border-color: var(--red); background: var(--red-soft); }
.outcome-grid { display: grid; grid-template-columns: 1fr 1fr; gap: 12px; }
.economic-shell { display: grid; grid-template-columns: 0.9fr 1.1fr; gap: 20px; margin-top: 22px; padding: 26px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel); }
.economic-shell > article p { color: var(--soft); }
.evidence-note, .frontier-rule, .research-warning { padding: 14px 16px; border-left: 4px solid var(--amber); background: var(--amber-soft); color: var(--soft); }
.cost-calculator { display: grid; gap: 14px; }
.cost-calculator fieldset { display: grid; grid-template-columns: repeat(3, 1fr); gap: 10px; margin: 0; padding: 16px; border: 1px solid var(--line); border-radius: var(--radius-sm); }
.cost-calculator legend { padding: 0 7px; color: var(--red); font-weight: 900; }
.cost-calculator label { color: var(--soft); font-size: 0.8rem; font-weight: 750; }
input[type="number"] { width: 100%; min-height: 44px; margin-top: 6px; padding: 9px 11px; border: 1px solid var(--line-strong); border-radius: 10px; color: var(--text); background: var(--bg); }
.cost-result { min-height: 58px; display: block; padding: 14px; border: 1px solid var(--line); border-radius: 12px; color: var(--soft); background: var(--panel-2); }

.tool-layout, .refractory-layout { display: grid; grid-template-columns: minmax(0, 1.12fr) minmax(330px, 0.88fr); gap: 18px; align-items: start; }
.triage-panel, .triage-result, .timeline-panel, .phenotype-detail, .audit-panel, .audit-result, .source-control-box, .discharge-checklist { border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel); box-shadow: var(--shadow); }
.triage-panel { padding: 24px; }
.triage-panel fieldset { margin: 0 0 18px; padding: 0; border: 0; }
.triage-panel legend { width: 100%; margin-bottom: 8px; padding-bottom: 8px; border-bottom: 1px solid var(--line); color: var(--red); font-weight: 900; }
.check-row { display: flex; gap: 10px; align-items: flex-start; padding: 9px 10px; border-radius: 10px; color: var(--soft); cursor: pointer; }
.check-row:hover, .audit-row:hover { background: var(--panel-2); }
.check-row.critical { color: var(--red); }
input[type="checkbox"] { flex: 0 0 auto; width: 19px; height: 19px; margin-top: 2px; accent-color: var(--red-dark); }
.triage-result, .audit-result { position: sticky; top: 112px; min-height: 280px; padding: 28px; border-color: var(--line-strong); }
.triage-result[data-level="critical"], .audit-result[data-level="open"] { border-color: var(--red); background: linear-gradient(145deg, var(--red-soft), var(--panel)); }
.triage-result[data-level="urgent"] { border-color: var(--amber); }
.triage-result[data-level="watch"], .audit-result[data-level="complete"] { border-color: var(--green); }
.status-pill { display: inline-flex; padding: 6px 10px; border: 1px solid var(--line-strong); border-radius: 999px; color: var(--red); font: 850 0.7rem/1 var(--mono); letter-spacing: 0.05em; text-transform: uppercase; }
.triage-result h3, .audit-result h3 { margin: 18px 0 9px; font-size: 1.55rem; }
.triage-result ol { padding-left: 20px; }
.definition-grid, .hemo-rules, .strategy-grid, .vasopressor-ladder, .organ-grid, .prevention-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: 14px; margin-top: 20px; }
.definition-card, .hemo-rules article, .strategy-card, .vasopressor-ladder article, .organ-card, .prevention-grid article { padding: 20px; border: 1px solid var(--line); border-radius: var(--radius-sm); background: var(--panel); }
.definition-card > span, .rule-tag, .vasopressor-ladder article > span, .recovery-track article > span { color: var(--red); font: 850 0.7rem/1 var(--mono); letter-spacing: 0.06em; text-transform: uppercase; }
.definition-card h3 { margin: 9px 0; }
.definition-card p, .hemo-rules p, .strategy-card p, .vasopressor-ladder p, .organ-card p, .prevention-grid p { margin-bottom: 0; color: var(--soft); }
.danger-card { border-color: var(--red); background: var(--red-soft); }
.table-scroll { margin-top: 20px; overflow-x: auto; border: 1px solid var(--line); border-radius: var(--radius-sm); }
table { width: 100%; min-width: 820px; border-collapse: collapse; background: var(--panel); font-size: 0.84rem; }
caption { padding: 14px; color: var(--muted); text-align: left; font-weight: 850; }
th, td { padding: 13px; border-top: 1px solid var(--line); text-align: left; vertical-align: top; }
th { color: var(--red); background: var(--panel-2); }
td { color: var(--soft); }
td:first-child { color: var(--text); font-weight: 850; }
tbody th { color: var(--text); background: var(--panel); font-weight: 850; }

.timeline-tabs, .phenotype-buttons, .layer-switcher { display: flex; gap: 8px; flex-wrap: wrap; margin-bottom: 14px; }
.timeline-tabs button, .phenotype-buttons button, .layer-button { border-radius: 999px; color: var(--soft); }
.timeline-tabs button.active, .phenotype-buttons button.active, .layer-button.active, .filter-button.active, .training-tab.active { color: #27070d; border-color: var(--red); background: var(--red); }
.timeline-panel { padding: 29px; }
.timeline-panel .time-badge { color: var(--red); font: 900 0.78rem/1 var(--mono); letter-spacing: 0.08em; text-transform: uppercase; }
.timeline-panel h3 { margin: 13px 0 8px; font-size: 1.75rem; }
.timeline-panel ul { padding-left: 21px; }
.timeline-panel li + li { margin-top: 8px; }
.reassess-line, .never-line { margin-top: 16px; padding: 13px 15px; }
.reassess-line { border-left: 4px solid var(--green); background: var(--green-soft); }
.never-line { border-left: 4px solid var(--red); background: var(--red-soft); }
.antibiotic-framework { display: grid; grid-template-columns: repeat(3, 1fr); gap: 13px; margin-top: 18px; }
.probability-card { padding: 20px; border: 1px solid var(--line); border-top-width: 4px; border-radius: var(--radius-sm); background: var(--panel); }
.probability-card span, .probability-card strong { display: block; }
.probability-card span { color: var(--muted); font-size: 0.78rem; font-weight: 800; text-transform: uppercase; }
.probability-card strong { margin: 9px 0; font-size: 1.12rem; }
.probability-card p { margin-bottom: 0; color: var(--soft); }
.probability-card.red { border-top-color: var(--red); }
.probability-card.amber { border-top-color: var(--amber); }
.probability-card.green { border-top-color: var(--green); }

.strategy-grid { grid-template-columns: repeat(3, 1fr); }
.strategy-card b { width: 31px; height: 31px; display: grid; place-items: center; border-radius: 50%; color: #27070d; background: var(--red); font-family: var(--mono); }
.strategy-card h3 { margin: 12px 0 7px; }
.source-control-box { display: grid; grid-template-columns: 0.9fr 1.1fr; gap: 24px; margin-top: 20px; padding: 26px; border-color: var(--red); background: linear-gradient(145deg, var(--red-soft), var(--panel)); }
.source-control-box ol { margin: 0; padding-left: 22px; }
.source-control-box li + li { margin-top: 7px; }

.hemo-rules { grid-template-columns: repeat(4, 1fr); }
.rule-tag { display: inline-block; margin-bottom: 10px; }
.rule-tag.strong { color: var(--green); }
.rule-tag.conditional { color: var(--amber); }
.reassessment-loop { display: grid; grid-template-columns: repeat(5, 1fr); margin: 20px 0; border: 1px solid var(--line); border-radius: var(--radius); overflow: hidden; background: var(--panel); }
.reassessment-loop div { padding: 18px; border-right: 1px solid var(--line); }
.reassessment-loop div:last-child { border-right: 0; }
.reassessment-loop b, .reassessment-loop span { display: block; }
.reassessment-loop b { color: var(--cyan); }
.reassessment-loop span { margin-top: 7px; color: var(--soft); font-size: 0.82rem; }
.vasopressor-ladder { grid-template-columns: repeat(4, 1fr); }

.phenotype-detail { padding: 28px; }
.phenotype-detail header { display: flex; gap: 15px; align-items: center; margin-bottom: 18px; }
.phenotype-icon { width: 56px; height: 56px; display: grid; place-items: center; flex: 0 0 auto; border: 1px solid var(--line-strong); border-radius: 17px; color: var(--red); background: var(--panel-2); font: 900 1.55rem/1 var(--mono); }
.phenotype-detail h3 { margin-bottom: 4px; font-size: 1.7rem; }
.phenotype-detail header p { margin: 0; color: var(--muted); }
.phenotype-mechanism { padding: 15px; border-left: 4px solid var(--cyan); background: rgba(101, 217, 242, 0.07); }
.phenotype-columns { display: grid; grid-template-columns: 1fr 1fr; gap: 14px; margin-top: 14px; }
.phenotype-column { padding: 16px; border: 1px solid var(--line); border-radius: 12px; background: var(--panel-2); }
.phenotype-column b { color: var(--red); }
.phenotype-column ul { margin-bottom: 0; padding-left: 19px; }
.phenotype-trap { margin-top: 14px; padding: 14px; border-left: 4px solid var(--red); background: var(--red-soft); }
.phenotype-evidence { margin: 13px 0 0; color: var(--muted); font-size: 0.82rem; }
.research-warning { margin-top: 15px; border-left-color: var(--red); background: var(--red-soft); }

.audit-panel { padding: 20px; }
.audit-panel fieldset { min-width: 0; margin: 0; padding: 0; border: 0; }
.audit-row { display: flex; gap: 11px; align-items: flex-start; padding: 12px; border-bottom: 1px solid var(--line); border-radius: 10px; color: var(--soft); cursor: pointer; }
.audit-row:last-child { border-bottom: 0; }
.audit-row b, .audit-row span { display: block; }
.audit-row > span { min-width: 0; max-width: 100%; flex: 1 1 auto; overflow-wrap: anywhere; }
.audit-row b { color: var(--text); }

.organ-grid { grid-template-columns: repeat(4, 1fr); }
.organ-card .organ-icon { font-size: 1.8rem; }
.organ-card h3 { margin: 9px 0; }
.organ-limit { margin-top: 12px; padding-top: 11px; border-top: 1px solid var(--line); color: var(--amber) !important; font-size: 0.82rem; }

.filter-row { margin-bottom: 16px; }
.filter-button, .training-tab { color: var(--soft); }
.frontier-grid { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 14px; }
.frontier-card { padding: 21px; border: 1px solid var(--line); border-left-width: 4px; border-radius: var(--radius-sm); background: var(--panel); }
.frontier-card[data-status="supported"] { border-left-color: var(--green); }
.frontier-card[data-status="insufficient"] { border-left-color: var(--amber); }
.frontier-card[data-status="against"] { border-left-color: var(--red); }
.frontier-card .evidence-badge { display: inline-flex; padding: 5px 8px; border: 1px solid var(--line-strong); border-radius: 999px; color: var(--amber); font: 850 0.68rem/1 var(--mono); letter-spacing: 0.04em; }
.frontier-card[data-status="supported"] .evidence-badge { color: var(--green); }
.frontier-card[data-status="against"] .evidence-badge { color: var(--red); }
.frontier-card h3 { margin: 13px 0 8px; }
.frontier-card p { color: var(--soft); }
.frontier-card .guardrail { margin-bottom: 0; padding: 12px; border-radius: 10px; background: var(--panel-2); font-size: 0.84rem; }
.frontier-rule { margin-top: 18px; }

.recovery-track { display: grid; grid-template-columns: repeat(4, 1fr); gap: 13px; }
.recovery-track article { padding: 20px; border: 1px solid var(--line); border-radius: var(--radius-sm); background: var(--panel); }
.recovery-track h3 { margin: 10px 0; }
.recovery-track ul { margin-bottom: 0; padding-left: 19px; color: var(--soft); }
.discharge-checklist { margin-top: 20px; padding: 24px; }
.checklist-grid { display: grid; grid-template-columns: 1fr 1fr; gap: 8px 18px; }
.checklist-grid label { display: flex; gap: 10px; align-items: flex-start; padding: 7px; color: var(--soft); }
.prevention-grid { grid-template-columns: repeat(4, 1fr); }
.prevention-grid b { color: var(--red); }

.radar-pipeline { display: grid; grid-template-columns: repeat(5, 1fr); border: 1px solid var(--line); border-radius: var(--radius); overflow: hidden; background: var(--panel); }
.radar-pipeline div { padding: 20px; border-right: 1px solid var(--line); }
.radar-pipeline div:last-child { border-right: 0; }
.radar-pipeline b { width: 30px; height: 30px; display: grid; place-items: center; border-radius: 50%; color: #27070d; background: var(--red); font-family: var(--mono); }
.radar-pipeline span, .radar-pipeline small { display: block; }
.radar-pipeline span { margin-top: 11px; color: var(--text); font-weight: 850; }
.radar-pipeline small { margin-top: 5px; color: var(--soft); }
.ai-boundary { display: grid; grid-template-columns: 0.7fr 1fr 1fr; gap: 13px; margin-top: 18px; }
.ai-boundary > * { padding: 18px; border: 1px solid var(--line); border-radius: var(--radius-sm); background: var(--panel); }
.ai-boundary p { margin-bottom: 0; color: var(--soft); }

.training-tabs { margin-bottom: 16px; }
.training-grid { display: grid; grid-template-columns: repeat(2, 1fr); gap: 15px; }
.quiz-card { padding: 22px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel); }
.quiz-card .quiz-meta { color: var(--red); font: 850 0.7rem/1 var(--mono); letter-spacing: 0.06em; text-transform: uppercase; }
.quiz-card h3 { margin: 12px 0; }
.quiz-options { display: grid; gap: 8px; }
.quiz-option { width: 100%; min-height: 44px; padding: 11px 13px; border: 1px solid var(--line); border-radius: 11px; color: var(--text); background: var(--bg); text-align: left; cursor: pointer; }
.quiz-option:hover { border-color: var(--red); }
.quiz-option.correct { border-color: var(--green); background: var(--green-soft); }
.quiz-option.incorrect { border-color: var(--red); background: var(--red-soft); }
.quiz-feedback { margin-top: 9px; padding: 11px; border-radius: 10px; color: var(--soft); background: var(--panel-2); }
.quiz-pearl { margin: 13px 0 0; padding: 11px; border-left: 4px solid var(--amber); background: var(--amber-soft); }

.reference-list { display: grid; gap: 10px; }
.reference-card { display: grid; grid-template-columns: 145px minmax(0, 1fr) auto; gap: 16px; align-items: center; padding: 17px; border: 1px solid var(--line); border-radius: 14px; background: var(--panel); }
.reference-meta { color: var(--red); font: 850 0.72rem/1.3 var(--mono); text-transform: uppercase; }
.reference-card h3 { margin: 0 0 5px; font-size: 1rem; }
.reference-card p { margin: 0; color: var(--muted); font-size: 0.82rem; }
.reference-card .reference-limit { margin-top: 5px; color: var(--amber); }
.reference-card a { color: var(--red); font-weight: 850; white-space: nowrap; }

.gate-section { border-top: 1px solid var(--line); background: var(--bg-soft); }
.gate-grid { display: grid; grid-template-columns: repeat(4, 1fr); gap: 13px; }
.gate-grid article { display: grid; gap: 7px; padding: 18px; border: 1px solid var(--line); border-radius: var(--radius-sm); background: var(--panel); }
.gate-grid span { color: var(--red); font: 850 0.7rem/1 var(--mono); text-transform: uppercase; }
.gate-grid strong { color: var(--muted); font-size: 0.8rem; }
.gate-grid .gate-current { color: var(--amber); }

footer { padding: 46px 0; border-top: 1px solid var(--line); background: var(--bg-soft); }
.footer-grid { display: grid; grid-template-columns: 1fr auto; gap: 28px; }
.footer-grid p { max-width: 680px; color: var(--muted); }
.footer-grid > div:last-child { display: grid; gap: 7px; align-content: start; }
.footer-grid a { color: var(--red); font-weight: 750; }

@media (max-width: 1050px) {
  .nav-shell { align-items: flex-start; padding-block: 12px; }
  .menu-button { display: inline-flex; align-items: center; }
  .nav-links { display: none; position: absolute; inset: 76px 12px auto; padding: 12px; border: 1px solid var(--line-strong); border-radius: 14px; background: var(--panel); box-shadow: var(--shadow); }
  .nav-links.open { display: flex; }
  .hero-grid, .tool-layout, .refractory-layout, .economic-shell { grid-template-columns: minmax(0, 1fr); }
  .hero-grid > *, .tool-layout > *, .refractory-layout > *, .economic-shell > * { min-width: 0; max-width: 100%; }
  .triage-result, .audit-result { position: static; }
  .how-grid { grid-template-columns: repeat(2, 1fr); }
  .command-grid, .reassessment-loop, .radar-pipeline { grid-template-columns: repeat(2, 1fr); }
  .command-grid div, .reassessment-loop div, .radar-pipeline div { border-bottom: 1px solid var(--line); }
  .hemo-rules, .vasopressor-ladder, .organ-grid, .prevention-grid, .recovery-track { grid-template-columns: repeat(2, 1fr); }
  .acra-mode-dock__inner { grid-template-columns: minmax(0, 1fr); gap: 8px; padding-block: 12px; }
  .visual-grid--2, .visual-grid--3 { grid-template-columns: minmax(0, 1fr); }
  .acra-slot-grid { grid-template-columns: minmax(0, 1fr); }
}

@media (max-width: 720px) {
  .source-cloud { grid-template-columns: repeat(2, minmax(0, 1fr)); }
  .wrap { width: min(var(--max), calc(100% - 22px)); }
  .review-strip .wrap, .section-heading { display: block; }
  .review-strip span { display: block; margin-top: 3px; }
  .hero { padding-top: 50px; }
  h1 { font-size: clamp(3.1rem, 18vw, 5rem); }
  .section { padding: 62px 0; }
  .how-grid, .command-grid, .definition-grid, .strategy-grid, .hemo-rules, .vasopressor-ladder, .organ-grid, .frontier-grid, .recovery-track, .prevention-grid, .training-grid, .gate-grid, .outcome-grid, .phenotype-columns, .checklist-grid, .radar-pipeline, .ai-boundary, .antibiotic-framework { grid-template-columns: minmax(0, 1fr); }
  .antibiotic-framework > *, .table-scroll { min-width: 0; max-width: 100%; }
  .command-grid div, .reassessment-loop div, .radar-pipeline div { border-right: 0; }
  .counter-grid { grid-template-columns: 1fr; }
  .cost-calculator fieldset { grid-template-columns: 1fr; }
  .source-control-box { grid-template-columns: 1fr; }
  .reassessment-loop { grid-template-columns: 1fr; }
  .reference-card { grid-template-columns: 1fr; }
  .reference-card a { white-space: normal; }
  .brand small { display: none; }
  .acra-mode-dock { position: static; }
  .visual-grid--2, .visual-grid--3 { grid-template-columns: 1fr; }
  .acra-slot { width: 100%; max-width: 100%; grid-template-columns: minmax(0, 1fr); gap: 14px; }
  .acra-slot__actions { min-width: 0; width: 100%; }
  .acra-runtime { grid-template-columns: minmax(0, 1fr); gap: 13px; padding: 15px; }
  .acra-runtime__critical, .acra-runtime__cards, .acra-runtime__actions, .acra-runtime__key-values { grid-template-columns: minmax(0, 1fr); }
  .acra-runtime__critical-item, .acra-runtime__component, .acra-runtime__card, .acra-runtime__question { padding: 13px; }
  .acra-runtime__table { min-width: 38rem; }
  .dialog-shell { padding: 14px; }
  .dialog-toolbar { top: -14px; margin: -14px -14px 14px; padding: 11px 13px; }
  .acra-stage__footer { align-items: flex-start; flex-direction: column; }
}

@media (max-width: 420px) {
  .source-cloud { grid-template-columns: minmax(0, 1fr); }
}

@media (max-width: 360px) {
  .wrap { width: min(var(--max), calc(100% - 16px)); }
  .acra-mode-buttons, .acra-mode-buttons button, .acra-slot__actions .button { width: 100%; }
  .visual-zoom { right: 8px; bottom: 8px; padding-inline: 10px; }
  .clinical-visual figcaption, .acra-slot { padding: 14px; }
  .visual-actions, .visual-full-link, .visual-download { width: 100%; }
  .visual-full-link, .visual-download { justify-content: center; }
  .acra-runtime { padding: 12px; border-radius: 14px; }
  .acra-runtime__critical-item, .acra-runtime__component, .acra-runtime__card, .acra-runtime__question { padding: 11px; }
  .acra-runtime__tab { max-width: calc(100vw - 72px); }
  .dialog-toolbar { align-items: flex-start; }
  .dialog-toolbar .eyebrow { max-width: 150px; }
}

@media print {
  :root, html[data-theme="dark"], html[data-theme="light"], html.a11y-contrast {
    color-scheme: light;
    --bg: #ffffff;
    --bg-soft: #ffffff;
    --panel: #ffffff;
    --panel-2: #f4f4f4;
    --text: #111111;
    --soft: #2f2f2f;
    --muted: #4b4b4b;
    --line: #8b8b8b;
    --line-strong: #555555;
    --red: #8f1831;
    --amber: #805300;
    --green: #087857;
    --cyan: #006a7d;
    --shadow: none;
  }
  body, .hero, .section, .section-soft, .command-band, footer { background: #ffffff !important; color: #111111 !important; }
  .topbar, .review-strip, .acra-mode-dock, .acra-slot, dialog, .visual-zoom, .visual-full-link, .visual-download, .hero-actions, .menu-button, .control-button, .form-actions, .filter-row, .training-tabs, .gate-section { display: none !important; }
  .mortality-card, .triage-panel, .triage-result, .timeline-panel, .phenotype-detail, .audit-panel, .audit-result, .quiz-card, .reference-card, .organ-card, .frontier-card { box-shadow: none !important; break-inside: avoid; }
  .section { padding: 1.1rem 0; }
  .clinical-visual { break-inside: avoid; box-shadow: none; }
  .visual-description > p { display: block !important; }
  a { color: #111111; text-decoration: underline; }
}

@media (prefers-reduced-motion: reduce) {
  *, *::before, *::after { scroll-behavior: auto !important; transition: none !important; animation: none !important; }
}

/* SEPSE-UI-REVIEW-FIX-V3 */
.pathway-universe .source-cloud {
  width: min(940px, 100%) !important;
  display: grid !important;
  grid-template-columns: repeat(3, minmax(0, 1fr)) !important;
  gap: 10px !important;
  margin-inline: auto !important;
  align-items: stretch !important;
}
.pathway-universe .source-cloud > span {
  min-width: 0 !important;
  min-height: 48px !important;
  display: flex !important;
  align-items: center !important;
  justify-content: center !important;
  padding: 10px 12px !important;
  border-radius: 13px !important;
  text-align: center !important;
  white-space: normal !important;
}
.acra-stage .acra-stage__shell {
  min-height: 0 !important;
}
.acra-stage [data-acra-stage-content] {
  min-height: 0 !important;
  max-height: calc(100dvh - 300px) !important;
  overflow: auto !important;
}
.acra-stage [data-acra-stage-content] > .acra-runtime {
  margin-top: 16px !important;
}
@media (max-width: 760px) {
  .pathway-universe .source-cloud {
    grid-template-columns: repeat(2, minmax(0, 1fr)) !important;
  }
}
@media (max-width: 430px) {
  .pathway-universe .source-cloud {
    grid-template-columns: minmax(0, 1fr) !important;
  }
}
/* /SEPSE-UI-REVIEW-FIX-V3 */

/* SEPSE-ORGAN-SYSTEMS-FINAL */
#sepse-organ-systems-grid {
  width: min(940px, 100%) !important;
  display: grid !important;
  grid-template-columns: repeat(3, minmax(0, 1fr)) !important;
  gap: 10px !important;
  margin-inline: auto !important;
  align-items: stretch !important;
}
#sepse-organ-systems-grid > span {
  min-width: 0 !important;
  min-height: 48px !important;
  display: flex !important;
  align-items: center !important;
  justify-content: center !important;
  padding: 10px 12px !important;
  border-radius: 13px !important;
  text-align: center !important;
  white-space: normal !important;
}
@media (max-width: 760px) {
  #sepse-organ-systems-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr)) !important;
  }
}
@media (max-width: 430px) {
  #sepse-organ-systems-grid {
    grid-template-columns: minmax(0, 1fr) !important;
  }
}
/* /SEPSE-ORGAN-SYSTEMS-FINAL */