:root {
  color-scheme: dark;
  --bg: #051216;
  --bg-soft: #091f26;
  --panel: #0d272e;
  --panel-2: #12343d;
  --text: #f5fffd;
  --soft: #c1d8d4;
  --muted: #8eaaa7;
  --line: rgba(197, 239, 231, 0.16);
  --line-strong: rgba(197, 239, 231, 0.3);
  --mint: #54e6c0;
  --mint-dark: #0ba980;
  --amber: #ffc857;
  --danger: #ff6b7a;
  --danger-soft: rgba(255, 107, 122, 0.12);
  --violet: #b9a2ff;
  --shadow: 0 24px 70px rgba(0, 0, 0, 0.32);
  --radius: 22px;
  --radius-sm: 14px;
  --max: 1220px;
  --sans: Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;
  --mono: ui-monospace, SFMono-Regular, Menlo, Monaco, Consolas, monospace;
}

html[data-theme="light"] {
  color-scheme: light;
  --bg: #ffffff;
  --bg-soft: #eef8f6;
  --panel: #ffffff;
  --panel-2: #e3f3ef;
  --text: #102d31;
  --soft: #355c60;
  --muted: #5d777a;
  --line: #9db7b5;
  --line-strong: #6e9190;
  --mint: #087f64;
  --mint-dark: #06634f;
  --amber: #875900;
  --danger: #b4233d;
  --danger-soft: #fff1f3;
  --violet: #654ac1;
  --shadow: 0 18px 50px rgba(32, 86, 80, 0.12);
}

html.a11y-contrast {
  color-scheme: dark;
  --bg: #000000;
  --bg-soft: #000000;
  --panel: #000000;
  --panel-2: #111111;
  --text: #ffffff;
  --soft: #ffffff;
  --muted: #ffffff;
  --line: #ffffff;
  --line-strong: #ffffff;
  --mint: #00ffb7;
  --mint-dark: #00ffb7;
  --amber: #ffe600;
  --danger: #ff7890;
  --danger-soft: #000000;
  --violet: #dccaff;
  --shadow: none;
}

* { box-sizing: border-box; }
html { scroll-behavior: smooth; scroll-padding-top: 118px; }
body {
  margin: 0;
  min-width: 320px;
  font-family: var(--sans);
  color: var(--text);
  line-height: 1.55;
  background:
    radial-gradient(circle at 10% 0, rgba(84, 230, 192, 0.12), transparent 28rem),
    radial-gradient(circle at 92% 18%, rgba(185, 162, 255, 0.09), transparent 24rem),
    var(--bg);
}
body.focus-mode .section:not(:target),
body.focus-mode .safety-band,
body.focus-mode footer { opacity: 0.38; }
body.focus-mode .section:target { opacity: 1; }
button, input, select { font: inherit; }
a { color: inherit; }
button, a, input, select { -webkit-tap-highlight-color: transparent; }
:where(button, a, input, select, [tabindex]):focus-visible { outline: 3px solid var(--amber); outline-offset: 3px; }
.wrap { width: min(var(--max), calc(100% - 32px)); margin-inline: auto; }
.skip-link { position: fixed; z-index: 100; top: -70px; left: 14px; padding: 10px 14px; background: var(--text); color: var(--bg); border-radius: 10px; font-weight: 900; }
.skip-link:focus { top: 12px; }

.topbar { position: sticky; z-index: 50; top: 0; border-bottom: 1px solid var(--line); background: rgba(5, 18, 22, 0.92); backdrop-filter: blur(18px); }
html[data-theme="light"] .topbar { background: rgba(255, 255, 255, 0.94); }
.nav-shell { min-height: 76px; display: flex; align-items: center; justify-content: space-between; gap: 24px; }
.brand { display: flex; align-items: center; gap: 11px; min-width: max-content; text-decoration: none; }
.brand-icon { width: 46px; height: 46px; display: grid; place-items: center; border: 1px solid var(--line-strong); border-radius: 15px; background: var(--panel-2); font-size: 1.35rem; }
.brand strong, .brand small { display: block; }
.brand strong { letter-spacing: -0.02em; }
.brand small { margin-top: 2px; color: var(--muted); font: 0.66rem/1.2 var(--mono); letter-spacing: 0.08em; text-transform: uppercase; }
.nav-links { display: flex; align-items: center; justify-content: flex-end; gap: 5px; flex-wrap: wrap; }
.nav-links a, .control-button { padding: 8px 10px; color: var(--soft); border: 1px solid transparent; border-radius: 10px; background: transparent; text-decoration: none; font-size: 0.82rem; font-weight: 750; cursor: pointer; }
.nav-links a:hover, .control-button:hover, .control-button[aria-pressed="true"] { color: var(--text); border-color: var(--line-strong); background: var(--panel-2); }
.official-strip { padding: 8px 0; color: #05241e; background: var(--mint); }
.official-strip .wrap { display: flex; justify-content: space-between; gap: 18px; font-size: 0.78rem; }
.official-strip strong { text-transform: uppercase; letter-spacing: 0.06em; }

.hero { padding: 78px 0 62px; }
.hero-grid { display: grid; grid-template-columns: minmax(0, 1.35fr) minmax(300px, 0.65fr); gap: 44px; align-items: center; }
.eyebrow { display: inline-block; color: var(--mint); font: 800 0.73rem/1.2 var(--mono); letter-spacing: 0.1em; text-transform: uppercase; }
h1, h2, h3, p { margin-top: 0; }
h1 { max-width: 820px; margin-bottom: 22px; font-size: clamp(2.8rem, 7vw, 6.2rem); line-height: 0.98; letter-spacing: -0.058em; }
h1 em { color: var(--mint); font-style: normal; }
h2 { margin-bottom: 0; font-size: clamp(2rem, 4.2vw, 3.5rem); line-height: 1.03; letter-spacing: -0.045em; }
h3 { line-height: 1.18; letter-spacing: -0.02em; }
.hero-lead { max-width: 760px; color: var(--soft); font-size: 1.18rem; }
.hero-actions { display: flex; gap: 10px; flex-wrap: wrap; margin: 28px 0 16px; }
.button { display: inline-flex; align-items: center; justify-content: center; min-height: 44px; padding: 10px 15px; border: 1px solid var(--line-strong); border-radius: 12px; color: var(--text); background: var(--panel); text-decoration: none; font-weight: 850; cursor: pointer; }
.button:hover { transform: translateY(-1px); border-color: var(--mint); }
.button-primary { color: #06251e; border-color: var(--mint); background: var(--mint); }
.button-ghost { color: var(--muted); background: transparent; }
.microcopy { max-width: 700px; color: var(--muted); font-size: 0.82rem; }
.red-flag-card { position: relative; padding: 28px; overflow: hidden; border: 1px solid rgba(255, 107, 122, 0.5); border-radius: var(--radius); background: linear-gradient(145deg, var(--danger-soft), var(--panel)); box-shadow: var(--shadow); }
.red-flag-card::after { content: ""; position: absolute; width: 160px; height: 160px; top: -80px; right: -70px; border-radius: 50%; background: rgba(255, 107, 122, 0.16); filter: blur(8px); }
.red-flag-card > * { position: relative; z-index: 1; }
.red-flag-card strong { display: block; margin: 13px 0; color: var(--danger); font-size: 1.3rem; line-height: 1.25; }
.red-flag-card ul { margin: 16px 0 0; padding-left: 20px; color: var(--soft); }
.pulse-dot { display: inline-block; width: 11px; height: 11px; border-radius: 50%; background: var(--danger); box-shadow: 0 0 0 8px rgba(255, 107, 122, 0.1); }

.safety-band { border-block: 1px solid var(--line); background: var(--bg-soft); }
.safety-grid { display: grid; grid-template-columns: repeat(4, 1fr); }
.safety-grid div { padding: 22px; border-right: 1px solid var(--line); }
.safety-grid div:last-child { border-right: 0; }
.safety-grid b, .safety-grid span { display: block; }
.safety-grid b { color: var(--mint); }
.safety-grid span { margin-top: 6px; color: var(--soft); font-size: 0.86rem; }

.section { padding: 86px 0; }
.section-tint { border-block: 1px solid var(--line); background: var(--bg-soft); }
.section-heading { display: flex; justify-content: space-between; align-items: end; gap: 36px; margin-bottom: 34px; }
.section-heading > p { max-width: 540px; margin-bottom: 2px; color: var(--soft); }
.how-to-section { padding-block: 68px; }
.how-to-grid { display: grid; grid-template-columns: repeat(5, minmax(0, 1fr)); gap: 12px; margin: 0; padding: 0; list-style: none; }
.how-to-grid a { min-height: 100%; display: flex; gap: 12px; padding: 18px; border: 1px solid var(--line); border-radius: var(--radius-sm); color: var(--soft); background: var(--panel); text-decoration: none; }
.how-to-grid a:hover { border-color: var(--mint); transform: translateY(-1px); }
.how-to-grid b { flex: 0 0 auto; width: 30px; height: 30px; display: grid; place-items: center; border-radius: 50%; color: #06251e; background: var(--mint); font-family: var(--mono); }
.how-to-grid span, .how-to-grid strong { display: block; }
.how-to-grid strong { margin-bottom: 5px; color: var(--text); line-height: 1.2; }
.how-to-grid span { font-size: 0.84rem; }
.tool-layout { display: grid; grid-template-columns: minmax(0, 1.1fr) minmax(330px, 0.9fr); gap: 18px; align-items: start; }
.tool-panel, .result-panel, .timeline-panel, .phenotype-detail, .drug-clock, .scorten-layout, .therapy-panel, .universal-care, .transfer-call, .training-shell { border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel); box-shadow: var(--shadow); }
.tool-panel { padding: 24px; }
fieldset { margin: 0 0 18px; padding: 0; border: 0; }
legend { width: 100%; margin-bottom: 8px; padding-bottom: 8px; border-bottom: 1px solid var(--line); color: var(--mint); font-weight: 900; }
.check-row { display: flex; gap: 10px; align-items: flex-start; padding: 9px 10px; border-radius: 10px; color: var(--soft); cursor: pointer; }
.check-row:hover { background: var(--panel-2); }
.check-row.critical { color: var(--danger); }
input[type="checkbox"] { flex: 0 0 auto; width: 19px; height: 19px; margin-top: 2px; accent-color: var(--mint-dark); }
.form-actions { display: flex; gap: 8px; flex-wrap: wrap; }
.result-panel { position: sticky; top: 112px; min-height: 300px; padding: 28px; border-color: var(--line-strong); }
.result-panel[data-level="critical"] { border-color: var(--danger); background: linear-gradient(145deg, var(--danger-soft), var(--panel)); }
.result-panel[data-level="urgent"] { border-color: var(--amber); }
.result-panel[data-level="watch"] { border-color: var(--mint); }
.result-state { display: inline-flex; padding: 5px 9px; border: 1px solid var(--line-strong); border-radius: 999px; color: var(--mint); font: 800 0.7rem/1 var(--mono); text-transform: uppercase; letter-spacing: 0.06em; }
.result-panel h3 { margin: 18px 0 10px; font-size: 1.65rem; }
.result-panel ol { padding-left: 21px; }
.result-panel li + li { margin-top: 7px; }
.result-alert { margin-top: 18px; padding: 13px; border-left: 4px solid var(--danger); background: var(--danger-soft); }

.timeline-tabs, .phenotype-switcher, .therapy-tabs, .training-nav { display: flex; gap: 8px; flex-wrap: wrap; margin-bottom: 14px; }
.timeline-tabs button, .phenotype-switcher button, .therapy-tabs button, .training-tab { padding: 10px 14px; border: 1px solid var(--line); border-radius: 999px; color: var(--soft); background: var(--panel); font-weight: 850; cursor: pointer; }
.timeline-tabs button.active, .phenotype-switcher button.active, .therapy-tabs button.active, .training-tab.active { color: #06251e; border-color: var(--mint); background: var(--mint); }
.timeline-panel { padding: 30px; }
.timeline-panel .time-badge { color: var(--mint); font: 900 0.78rem/1 var(--mono); text-transform: uppercase; letter-spacing: 0.08em; }
.timeline-panel h3 { margin: 12px 0 8px; font-size: 1.7rem; }
.timeline-panel ul { padding-left: 21px; }
.timeline-panel li + li { margin-top: 8px; }
.never-line { margin-top: 20px; padding: 13px 15px; border-left: 4px solid var(--danger); background: var(--danger-soft); }

.phenotype-detail { padding: 28px; margin-bottom: 18px; }
.phenotype-detail header { display: flex; align-items: center; gap: 14px; margin-bottom: 18px; }
.phenotype-icon { font-size: 2.2rem; }
.phenotype-detail h3 { margin-bottom: 4px; font-size: 1.65rem; }
.phenotype-detail header p { margin: 0; color: var(--muted); }
.detail-columns { display: grid; grid-template-columns: 1fr 1fr; gap: 16px; }
.detail-box { padding: 16px; border: 1px solid var(--line); border-radius: var(--radius-sm); background: var(--panel-2); }
.detail-box b { color: var(--mint); }
.detail-box ul { margin-bottom: 0; padding-left: 19px; }
.detail-box.trap { border-color: rgba(255, 107, 122, 0.48); }
.detail-box.trap b { color: var(--danger); }
.table-scroll { overflow-x: auto; border: 1px solid var(--line); border-radius: var(--radius-sm); }
table { width: 100%; min-width: 980px; border-collapse: collapse; background: var(--panel); font-size: 0.83rem; }
caption { padding: 14px; color: var(--muted); text-align: left; font-weight: 800; }
th, td { padding: 13px; border-top: 1px solid var(--line); text-align: left; vertical-align: top; }
th { color: var(--mint); background: var(--panel-2); }
td:first-child { color: var(--text); font-weight: 850; }

.drug-clock { display: grid; grid-template-columns: 0.9fr 1.1fr; overflow: hidden; }
.drug-form, .drug-result { padding: 28px; }
.drug-form { border-right: 1px solid var(--line); }
.drug-form label:not(.check-row) { display: block; margin-bottom: 16px; color: var(--soft); font-weight: 750; }
select, input[type="number"] { width: 100%; min-height: 46px; margin-top: 7px; padding: 10px 12px; border: 1px solid var(--line-strong); border-radius: 10px; color: var(--text); background: var(--bg); }
.drug-result h3 { font-size: 1.65rem; }
.window-meter { width: 100%; height: 12px; margin: 22px 0 10px; overflow: hidden; border: 1px solid var(--line); border-radius: 999px; background: var(--bg); appearance: none; }
.window-meter::-webkit-progress-bar { background: var(--bg); }
.window-meter::-webkit-progress-value { background: var(--mint); }
.window-meter::-moz-progress-bar { background: var(--mint); }
.warning-box { margin-top: 16px; padding: 15px 17px; border: 1px solid rgba(255, 107, 122, 0.48); border-radius: var(--radius-sm); background: var(--danger-soft); }

.scorten-layout { display: grid; grid-template-columns: 1.15fr 0.85fr; overflow: hidden; }
.scorten-form { padding: 25px; border-right: 1px solid var(--line); }
.score-row { display: flex; align-items: center; gap: 10px; padding: 10px; border-bottom: 1px solid var(--line); cursor: pointer; }
.score-row span { margin-left: auto; color: var(--mint); font-family: var(--mono); }
.scorten-form .button { margin-top: 18px; }
.score-result { display: flex; align-items: center; gap: 22px; padding: 30px; }
.score-number { flex: 0 0 auto; width: 96px; height: 96px; display: grid; place-items: center; border: 2px solid var(--mint); border-radius: 50%; color: var(--mint); font: 900 3rem/1 var(--mono); }
.score-result[data-risk="high"] .score-number { border-color: var(--danger); color: var(--danger); }
.score-result p { margin: 7px 0 0; color: var(--muted); font-size: 0.84rem; }

.therapy-panel { padding: 28px; }
.therapy-panel h3 { font-size: 1.7rem; }
.therapy-columns { display: grid; grid-template-columns: 1fr 1fr; gap: 16px; }
.therapy-column { padding: 17px; border: 1px solid var(--line); border-radius: var(--radius-sm); background: var(--panel-2); }
.therapy-column h4 { margin: 0 0 10px; color: var(--mint); }
.therapy-column ul { margin: 0; padding-left: 20px; }
.therapy-column li + li { margin-top: 7px; }
.monitor-row { display: flex; flex-wrap: wrap; gap: 7px; margin: 18px 0; }
.monitor-row span { padding: 6px 9px; border: 1px solid var(--line); border-radius: 999px; color: var(--soft); font-size: 0.78rem; }
.evidence-line { margin: 0; padding: 13px; border-left: 4px solid var(--amber); background: rgba(255, 200, 87, 0.08); }
.universal-care { margin-top: 22px; padding: 26px; }
.checklist-grid { display: grid; grid-template-columns: 1fr 1fr; gap: 8px 18px; }
.checklist-grid label { display: flex; gap: 10px; padding: 8px 0; color: var(--soft); }

.destination-grid { display: grid; grid-template-columns: repeat(2, 1fr); gap: 16px; }
.destination-card { padding: 23px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel); }
.destination-card header { display: flex; justify-content: space-between; align-items: center; gap: 12px; }
.destination-card h3 { margin: 0; font-size: 1.35rem; }
.destination-level { color: var(--danger); font: 800 0.7rem/1.2 var(--mono); text-transform: uppercase; }
.destination-card ul { margin-bottom: 0; padding-left: 20px; color: var(--soft); }
.destination-card li + li { margin-top: 6px; }
.transfer-call { margin-top: 20px; padding: 26px; border-color: var(--line-strong); }
.transfer-call ol { margin-bottom: 0; padding-left: 22px; }
.transfer-call li + li { margin-top: 8px; }

.training-shell { padding: 28px; }
.progress-track { height: 8px; margin-bottom: 25px; overflow: hidden; border-radius: 999px; background: var(--bg); }
.progress-track progress { display: block; width: 100%; height: 100%; border: 0; background: transparent; appearance: none; }
.progress-track progress::-webkit-progress-bar { background: var(--bg); }
.progress-track progress::-webkit-progress-value { background: linear-gradient(90deg, var(--mint), var(--violet)); }
.progress-track progress::-moz-progress-bar { background: var(--mint); }
.training-meta { display: flex; justify-content: space-between; gap: 12px; margin-bottom: 13px; color: var(--muted); font: 800 0.72rem/1.2 var(--mono); text-transform: uppercase; }
.training-shell h3 { font-size: 1.65rem; }
.case-stem { padding: 17px; border-left: 4px solid var(--mint); background: var(--panel-2); }
.answer-list { display: grid; gap: 9px; margin-top: 18px; }
.answer-option { width: 100%; padding: 13px 15px; border: 1px solid var(--line); border-radius: 12px; color: var(--text); background: var(--bg); text-align: left; cursor: pointer; }
.answer-option:hover { border-color: var(--mint); }
.answer-option.correct { border-color: var(--mint); background: rgba(84, 230, 192, 0.12); }
.answer-option.incorrect { border-color: var(--danger); background: var(--danger-soft); }
.option-feedback { display: none; margin: -3px 0 6px; padding: 11px 13px; border-radius: 10px; color: var(--soft); background: var(--panel-2); }
.option-feedback.visible { display: block; }
.pearl { margin-top: 17px; padding: 13px; border-left: 4px solid var(--amber); background: rgba(255, 200, 87, 0.08); }
.training-actions { display: flex; gap: 8px; flex-wrap: wrap; margin-top: 22px; }
.flashcard { min-height: 290px; display: grid; place-items: center; padding: 30px; border: 1px solid var(--line-strong); border-radius: var(--radius); background: linear-gradient(145deg, var(--panel-2), var(--panel)); text-align: center; cursor: pointer; }
.flashcard span { color: var(--mint); font: 800 0.72rem/1 var(--mono); text-transform: uppercase; letter-spacing: 0.08em; }
.flashcard h3 { max-width: 760px; margin: 18px 0 0; font-size: clamp(1.6rem, 4vw, 2.5rem); }
.flashcard.revealed h3 { color: var(--mint); }

.references-list { display: grid; gap: 10px; }
.reference-card { display: grid; grid-template-columns: 76px minmax(0, 1fr) auto; gap: 16px; align-items: center; padding: 17px; border: 1px solid var(--line); border-radius: 14px; background: var(--panel); }
.reference-year { color: var(--mint); font: 900 1rem/1 var(--mono); }
.reference-card h3 { margin: 0 0 4px; font-size: 1rem; }
.reference-card p { margin: 0; color: var(--muted); font-size: 0.82rem; }
.reference-card a { color: var(--mint); font-weight: 850; white-space: nowrap; }

footer { padding: 48px 0; border-top: 1px solid var(--line); background: var(--bg-soft); }
.footer-grid { display: grid; grid-template-columns: 1fr auto; gap: 28px; }
.footer-grid p { max-width: 650px; color: var(--muted); }
.footer-grid > div:last-child { display: grid; gap: 7px; align-content: start; }
.footer-grid a { color: var(--mint); font-weight: 750; }

@media (max-width: 980px) {
  .nav-shell { align-items: flex-start; padding-block: 12px; }
  .nav-links a { display: none; }
  .hero-grid, .tool-layout, .drug-clock, .scorten-layout { grid-template-columns: 1fr; }
  .how-to-grid { grid-template-columns: repeat(2, minmax(0, 1fr)); }
  .result-panel { position: static; }
  .drug-form, .scorten-form { border-right: 0; border-bottom: 1px solid var(--line); }
  .safety-grid { grid-template-columns: 1fr 1fr; }
  .safety-grid div:nth-child(2) { border-right: 0; }
  .safety-grid div:nth-child(-n+2) { border-bottom: 1px solid var(--line); }
}

@media (max-width: 720px) {
  .wrap { width: min(100% - 22px, var(--max)); }
  .official-strip .wrap, .section-heading { display: block; }
  .official-strip span { display: block; margin-top: 3px; }
  .hero { padding-top: 52px; }
  h1 { font-size: clamp(2.55rem, 14vw, 4.5rem); }
  .section { padding: 64px 0; }
  .section-heading > p { margin-top: 16px; }
  .safety-grid, .how-to-grid, .detail-columns, .therapy-columns, .checklist-grid, .destination-grid, .footer-grid { grid-template-columns: 1fr; }
  .safety-grid div { border-right: 0; border-bottom: 1px solid var(--line); }
  .safety-grid div:last-child { border-bottom: 0; }
  .score-result { align-items: flex-start; }
  .reference-card { grid-template-columns: 58px minmax(0, 1fr); }
  .reference-card a { grid-column: 2; }
  .brand small { display: none; }
  .control-button { padding: 8px; font-size: 0.75rem; }
}

@media (prefers-reduced-motion: reduce) {
  *, *::before, *::after { scroll-behavior: auto !important; transition: none !important; animation: none !important; }
}

@media print {
  :root, html[data-theme="light"], html[data-theme="dark"], html.a11y-contrast {
    color-scheme: light;
    --bg: #fff;
    --bg-soft: #fff;
    --panel: #fff;
    --panel-2: #f2f7f6;
    --text: #102d31;
    --soft: #355c60;
    --muted: #5d777a;
    --line: #9db7b5;
    --line-strong: #6e9190;
    --mint: #087f64;
    --danger: #a71934;
    --danger-soft: #fff;
    --amber: #6f4b00;
    --shadow: none;
  }
  body, .hero, .section, .section-tint, .safety-band { background: #fff !important; color: var(--text) !important; }
  .topbar, .official-strip, .hero-actions, .nav-links, .training-actions, .training-nav, .timeline-tabs, .phenotype-switcher, .therapy-tabs, footer { display: none !important; }
  .section { padding: 28px 0; break-before: auto; }
  .tool-layout, .drug-clock, .scorten-layout, .therapy-columns, .destination-grid { grid-template-columns: 1fr; }
  .result-panel, .tool-panel, .timeline-panel, .phenotype-detail, .drug-clock, .scorten-layout, .therapy-panel, .universal-care, .destination-card, .transfer-call, .training-shell { box-shadow: none; break-inside: avoid; }
  .result-panel { position: static; }
  a[href]::after { content: none; }
}